The appointment of Queiroz came almost two weeks after Otto Addo was sacked.
The first leg of the playoff ties will be played on February 17 and 18 while the return legs will take place on February 25 and 26.
Anatoliy Trubin sealed the victory for Benfica as the goalkeeper headed home a free kick.
Nunes became Wolves’ record signing when he joined from Sporting Lisbon for an initial £38 million last summer.
Richarlison’s first goals for Tottenham Hotspur helped them mark their return to the Champions League with a 2-0 victory over 10-man Olympique de Marseille on Wednesday.
Manchester City sailed through to the UEFA Champions League quarter-finals after a 0-0 draw with Sporting Lisbon.
Manchester City sailed through to the UEFA Champions League quarter-finals after a 0-0 draw with Sporting Lisbon.
