Preliminary findings from an Australian study suggest that traumatic brain injuries, including concussions, may lead to lasting changes in the brain.

According to the study, these changes remain detectable decades later, even among otherwise healthy adults.

Researchers found that participants with a history of TBI recorded higher mood dysfunction scores and showed reduced white matter integrity across multiple brain regions compared with those without prior head injuries.

They also exhibited a diminished sense of smell, as well as autonomic and gastrointestinal changes, according to a statement released Monday by the University of Adelaide.

The identified symptoms commonly correlate with an elevated risk of developing neurodegenerative conditions, including Parkinson’s disease, later in life.

The ongoing study, which involves more than 600 participants, seeks to uncover the biological mechanisms that may increase the likelihood of dementia or Parkinson’s disease following a TBI.

The researchers noted that traumatic brain injury is linked to approximately 15 per cent of dementia cases.

Even a single TBI can raise the risk of Parkinson’s disease by more than 50 per cent, they added.

The trial remains underway as scientists continue to examine how head injuries may contribute to long-term neurological decline. 

(Xinhua/NAN)