United shared points with Southampton, failing to bounce back from a devastating 7-0 defeat to Liverpool last week.
This victory becomes United’s thirteenth straight home win across all competitions this season.
This is Arsenal’s second defeat in the Premier League since the 3-2 to Manchester United at Old Trafford in September 2022.
Casemiro scored twice as Manchester United defeated 10-man Reading at Old Trafford to reach the fifth round of the FA Cup on Saturday night.
Manchester United completed their first season signing after goalkeeper Jack Butland joined them on a six-month loan from Crystal Palace.
The reports linking the Lobi Stars did not sit well with the Nigerian club and has subsequently denied the rumours in a statement on its verified Twitter page.
AFC Crewe took to their official Twitter page to announce their intention to sign the Real Madrid legend on a year-long permanent contract.
The five-time ballon d’or winner said in an interview that he felt betrayed by the club and had no respect for coach Eric Ten Hag.
Manchester United had travelled to London on the back of a five-game unbeaten streak.
Juan Mata signed a one-year contract with Galatasaray on a free transfer.
