The PFA Award is determined through votes cast by both present and former players.
With 15 goals and seven assists this season, De Bruyne won majority votes to beat Salah and other nominated players.
Pep Guardiola’s men took another step towards a fourth title in five seasons, stretching their lead over Liverpool.
Sadio Mane saved the day for Liverpool with a priceless second-half equaliser in a gripping 2-2 draw with leaders Manchester City on Sunday.
Manchester City will go into next week’s clash with Liverpool with a one-point lead.
Sunday’s humiliating defeat puts Ralf Rangnick’s United in fifth position with 47 points in 28 games behind Arsenal.
So far, City have garnered 56 points in 22 games, while Chelsea comes behind them with 43 points in 22 games.
In the second half, Leicester scored three goals in 10 minutes through Maddison, Lookman, and Iheanacho to threaten a stunning comeback.
Six-time winner Messi and five-time winner Ronaldo are pundits favourites to win this year’s Ballon d’Or.
On Sunday, Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter at Anfield.
